Curvilinearity in the dose-response curve for cancer in Japanese atomic bomb survivors.

Curvilinearity in the dose-response curve for cancer in Japanese atomic bomb survivors.

Recently released data on cancer incidence in Japanese atomic bomb survivors are analyzed using a variety of relative risk models that take account of errors in estimates of dose to assess the dose response at low doses. If a relative risk model with a threshold (the dose response is assumed linear above the threshold) is fitted to solid cancer data, a threshold of more than about 0.2 Sv is inc...

Accounting for neutron exposure in the Japanese atomic bomb survivors.

The Japanese atomic bomb survivors that were directly exposed to both γ rays and neutrons have been followed by the Radiation Effects Research Foundation (RERF). The estimation of the γ-ray risks requires some adjustment for the greater biological effect of the neutrons per unit dose. Because the small neutron doses and the predominant γ-ray doses are highly correlated, the neutron relative bio...

Glaucoma in atomic bomb survivors.

Radiation has been associated with increases in noncancerous diseases. An effect of low-dose radiation on the prevalence of clinically detected glaucoma has not been previously reported. We therefore investigated the prevalence of glaucoma in A-bomb survivors and its possible association with radiation dose. A total of 1,589 people who participated in the clinical examination program for A-bomb...

Leukemia in Atomic Bomb Survivors

EUKEMOGENESIS induced by repeated exposures to x-ray and other forms of radiation energy has long been recognized in man and in experimental ammals.’3 The explosion of the atomic bombs in Japan exposed two large human populations to single brief but massive doses of ionizing irradiation and subsequently a marked increase in leukemia among survivors was reported.4 ‘ The present study consists of...

Risks of non-cancer disease incidence and mortality in the Japanese atomic bomb survivors.